2023
Manzano-Marín A*, Coeur d’acier A, Clamens A-L, Cruaud C, Barbe V, and Jousselin E. Co-obligate symbioses have repeatedly evolved across aphids, but partner identity and nutritional contributions vary across lineages. Peer Community Journal, 3:e46. doi: 10.24072/pcjournal.278. bioRχiv: https://doi.org/10.1101/2022.08.28.505559.
Halter T, Köstlbacher S, Rattei T, Hendrickx F, Manzano-Marín A*, and Horn M. One to host them all: genomics of the diverse bacterial endosymbionts of the spider Oedothorax gibbosus. Microbial Genomics, 9(2):000943. doi: 10.1099/mgen.0.000943. bioRχiv: 10.1101/2022.05.31.494226.
2022
Halter T, Hendrickx F, Horn M, and Manzano-Marín A*. A novel widespread MITE element in the repeat-rich genome of the Cardinium endosymbiont of the spider Oedothorax gibbosus. Microbiology Spectrum, 10(6):e02627-22. doi: 10.1128/spectrum.02627-22. bioRχiv: 10.1101/2022.06.21.494476.
Smith G, Manzano-Marín A, Reyes-Prieto M, Ribeiro Antunes CS, Ashworth V, Goselle ON, Jan AAA, Moya A, Latorre A, Perotti MA*, and Braig HR. Human follicular mites: Ectoparasites becoming symbionts. Molecular Biology and Evolution, 39(6):msac125. doi: 10.1093/molbev/msac125. Shared 1st authorship.
→News coverage (selected): EurekAlert! (AAAS), BBC, The Guardian, COSMOS, IFL Science, BIG Think, New York Post, Discover, The Telegraph, NPR, National Geographic España, Le Monde, Der Standard, APA, FOCUS, ORF, Krone, Spektrum.
Vittecoq M*, Brazier L, Elguero E, Bravo IG, Renaud N, Manzano-Marín A, Prugnolle F, Godreuil S, Blanchon T, Roux F, Durand P, Renaud F, and Thomas F. Multiresistant Enterobacteriaceae in yellow‐legged gull chicks in their first weeks of life. Ecology and Evolution, 12(6):e8974. doi: 10.1002/ece3.8974. Dryad dataset: 10.5061/dryad.fxpnvx0vf.
Szabó G*, Schulz F, Manzano-Marín A, Toenshoff ER, and Horn M. Evolutionary recent dual obligatory symbiosis among adelgids indicates a transition between fungus and insect associated lifestyles. The ISME Journal, 16(1):247-256. doi: 10.1038/s41396-021-01056-z. bioRχiv: 10.1101/2020.10.16.342642.
2021
Ün C, Schultner E*, Manzano-Marín A, Flórez L, V, Heinze J, and Oettler J*. Cytoplasmic incompatibility between Old and New World populations of a tramp ant. Evolution, 75(7):1775-1791. doi: 10.1111/evo.14261. bioRχiv: 10.1101/2020.03.13.988675. Zenodo dataset: 10.5281/zenodo.3561160.
2020
Sosa-Jiménez VM, Torres-Carrera G, Manzano-Marín A, Kvist S, and Oceguera A*. Mitogenome of the blood feeding leech Haementeria acuecueyetzin (Hirudinida: Glossiphoniidae) from Tabasco, Mexico. Mitochondrial DNA Part B, 5(3):3328-3330. doi: 10.1080/23802359.2020.1814888.
Kvist S*, Manzano-Marín A, de Carle D, Trontelj P, and Siddall ME. Draft genome of the European medicinal leech Hirudo medicinalis (Annelida, Clitellata, Hirudiniformes) with emphasis on anticoagulants. Scientific Reports, 10(1):9885. doi: 10.1038/s41598-020-66749-5. Zenodo dataset: 10.5281/zenodo.3555585.
→News coverage: Forbes, EurekAlert! (AAAS), Phys.org, ScienMag, GenomeWeb, U.S. News & World Report, Drugs.com, HealthDay, DoctorsLounge, and Sci-News.com. Blogs: DNA Science Blog (PLoS) and Bioengineer.
Rouïl J, Jousselin E, Coeur d’acier A, Cruaud C, and Manzano-Marín A*. The protector within: Comparative genomics of APSE phages across aphids reveals rampant recombination and diverse toxin arsenals. Genome Biology and Evolution, 12(6):878-889. doi: 10.1093/gbe/evaa089. bioRχiv: 10.1101/2020.03.17.996009. Zenodo dataset: 10.5281/zenodo.3764739. Shared 1st authorship. PhD. student paper.
Manzano-Marín A*. No evidence for Wolbachia as a nutritional co-obligate endosymbiont in the aphid Pentalonia nigronervosa. Microbiome, 8:72. doi: 10.1186/s40168-020-00865-2. bioRχiv: 10.1101/609511. Zenodo dataset: 10.5281/zenodo.2640354. * Critical review showing contradictory results to those of de Clerck et. al. 2015 Microbiome 3(1): 63.
Manzano-Marín A*, Coeur d’acier A, Clamens A-L, Orvain C, Cruaud C, Barbe V, and Jousselin E. Serial horizontal transfer of vitamin-biosynthetic genes enables the establishment of new nutritional symbionts in aphids’ di-symbiotic systems. The ISME Journal, 14(1):259-273. doi: 10.1038/s41396-019-0533-6. bioRχiv: 10.1101/556274. Zenodo dataset: 10.5281/zenodo.2566355.
2019
Patel V, Chevignon G, Manzano-Marín A, Brandt JW, Strand MR, Russell JA, and Oliver KM*. Cultivation-assisted genome of Candidatus Fukatsuia symbiotica; the enigmatic 'X-type' symbiont of aphids. Genome Biology and Evolution, 11(12):3510-3522. doi: 10.1093/gbe/evz252.
2018
Manzano-Marín A*, Coeur d’acier A, Clamens A.-L, Orvain C, Cruaud C, Barbe V, and Jousselin E. A Freeloader? The highly eroded yet large genome of the Serratia symbiotica symbiont of Cinara strobi. Genome Biology and Evolution, 10(9):2178-2189. doi: 10.1093/gbe/evy173. bioRχiv: 10.1101/305458.
2017
Meseguer AS*, Manzano-Marín A, Coeur d’Acier A, Clamens A-L, Godefroid M, and Jousselin E. Buchnera has changed flatmate but the repeated replacement of co-obligate symbionts is not associated with the ecological expansions of their aphid hosts. Molecular Ecology, 26(8):2363-2378. doi: 10.1111/mec.13910. bioRχiv: 10.1101/086223. Perspective: 10.1111/mec.14047. PDF
Manzano-Marín A, Szabó G, Simon J-C, Horn M, and Latorre A*. Happens in the best of subfamilies: establishment and repeated replacements of co-obligate secondary endosymbionts within Lachninae aphids. Environmental Microbiology, 19(1):393-408. doi: 10.1111/1462-2920.13633. bioRχiv: 10.1101/059816. Highlighted: 10.1111/1462-2920.13516. PDF
2016
Manzano-Marín A* and Latorre A. Snapshots of a shrinking partner: Genome reduction in Serratia symbiotica. Scientific Reports, 6:32590. doi: 10.1038/srep32590. bioRχiv: 10.1101/057653.
Manzano-Marín A, Simon J.-C, and Latorre A*. Reinventing the wheel and making it round again: Evolutionary convergence in Buchnera-Serratia symbiotic consortia between the distantly related Lachninae aphids Tuberolachnus salignus and Cinara cedri. Genome Biology and Evolution, 8(5):1440-1458. doi: 10.1093/gbe/evw085.
Oceguera-Figueroa A*, Manzano-Marín A, Kvist S, Moya A, Siddall ME, and Latorre A. Comparative mitogenomics of leeches (Annelida: Clitellata): Genome conservation and Placobdella-specific trnD gene duplication. PLoS ONE, 11(5):e0155441. doi: 10.1371/journal.pone.0155441. Shared 1st authorship.
Klein A, Schrader L, Gil R, Manzano-Marín A, Flórez L, Wheeler D, Werren J. H, Latorre A, Heinze J, Kaltenpoth M, Moya A, and Oettler J*. A novel intracellular mutualistic bacterium in the invasive ant Cardiocondyla obscurior. The ISME Journal, 10(2):376-388. doi: 10.1038/ismej.2015.119.
2015
Manzano-Marín A, Oceguera-Figueroa A*, Latorre A, Jiménez-Garcı́a L. F, and Moya A. 2015. Solving a bloody mess: B-vitamin independent metabolic convergence among gammaproteobacterial obligate endosymbionts from blood-feeding arthropods and the leech Haementeria officinalis. Genome Biology and Evolution, 7(10):2871-2884. doi: 10.1093/gbe/evv188. Shared 1st authorship.
2014-2011
Manzano-Marín A and Latorre A*. Settling down: The genome of Serratia symbiotica from the aphid Cinara tujafilina zooms in on the process of accommodation to a cooperative intracellular life. Genome Biology and Evolution, 6(7):1683-1698. doi: 10.1093/gbe/evu133.
Manzano-Marín A, Lamelas A, Moya A, and Latorre A*. Comparative genomics of Serratia spp.: Two paths towards endosymbiotic life. PLoS ONE, 7(10):e47274. doi: 10.1371/journal.pone.0047274.
Lamelas A, Gosalbes M. J, Manzano-Marín A, Peretó J, Moya A, and Latorre A*. Serratia symbiotica from the aphid Cinara cedri: A missing link from facultative to obligate insect endosymbiont. PLoS Genetics, 7:e1002357. doi: 10.1371/journal.pgen.1002357.
2017
Latorre A and Manzano-Marín A. Dissecting genome reduction and trait loss in insect endosymbionts. Annals of the New York Academy of Sciences, 1389(1):52-75. doi: 10.1111/nyas.13222. PDF
2020
Monnin D et. al. Parallel evolution in the integration of a co-obligate aphid symbiosis. Current Biology, 30(10):1949-1957. doi: 10.1016/j.cub.2020.03.011.
The paper describes an independently evolved co-obligate symbiosis in Periphyllus aphids, but fails to provide compelling or conclusive evidence for A. urticata and M. carnosum. The full review can be read at PubPeer.
Invited
2022 | Over and over (again): Repeated evolution of co-obligate symbioses across aphids. 26th International Congress of Entomology. Helsinki, Finland. |
2018 | Buchnera’s sidekicks: The who and how of co-obligate nutritional symbioses across aphids. Final meeting of the PRC Israel-France. Sde Boker, Israel. |
2017 | The rise of co-obligate symbioses in aphids. Insect symbionts: Plasticity in confronting environmental challenges. Lyon, France. |
Oral
2018 | Manzano-Marín A, Coeur d’acier A, Clamens A-L, Orvain C, Cruaud C, Barbe V, and Jousselin E. Ongoing symbiont replacement in the aphid Cinara strobi. Recontres ALPHY/GTGC 2018. Montpellier, France. |
2017 | Manzano-Marín A, Coeur d’acier A, Clamens A-L, Orvain C, Cruaud C, Barbe V, and Jousselin E. Joining the team: Co-obligate symbionts of aphids evolving from distantly related bacteria. Annual meeting of the Society for Molecular Biology and Evolution 2017 (SMBE2017). Austin TX, USA. |
Manzano-Marín A, Coeur d’acier A, Clamens A-L, Orvain C, Cruaud C, Barbe V, and Jousselin E. The newcomers: distantly related bacteria have settled as co-obligate symbionts in aphids. 1st International conference on holobionts. Paris, France. | |
2015 | Manzano-Marín A, Szabo G, Simon J-C, Horn M, and Latorre A. No subfamily is perfect...: Secondary symbiont settlement, replacement and internalization in the subfamily Lachninae of aphids. 8th Congress of the International Symbiosis Society (ISS8). Lisboa, Portugal. |
2014 | Manzano-Marín A, Moya A, and Latorre A. Moving in: How Serratia symbiotica stopped playing the field and settled down with Buchnera. 15th International symposium on microbial ecology (ISME15). Seoul, South-Korea. |
Poster
2018 | Manzano-Marín A, Coeur d’acier A, Clamens A-L, Orvain C, Cruaud C, Barbe V, and Jousselin E. Coming and ceasing to be: Evolution of recent mutualistic associations in aphid endosymbionts. Evolution 2018. Montpellier, France. |
Manzano-Marín A, Coeur d’acier A, Clamens A-L, Orvain C, Cruaud C, Barbe V, and Jousselin E. The coming and gong of mutualistic symbionts: The ins and outs of co-obligate endosymbiont replacement in Cinara aphids. Annual Meeting of the Society for Molecular Biology and Evolution 2018 (SMBE2018). Yokohama, Japan. | |
2017 | Manzano-Marín A, Coeur d’acier A, Clamens A-L, Orvain C, Cruaud C, Barbe V, and Jousselin E. Bonding: Aphid’s co-obligate symbionts evolving from different bacterial taxa. Gordon Research Conference on animal-microbe symbioses - host-microbe associations at the foundation of the biosphere. Mount Snow, West Dover, United States of America. |
Manzano-Marín A, Coeur d’acier A, Clamens A-L, Orvain C, Cruaud C, Barbe V, and Jousselin E. Becoming obligate and small... fast!: Evolution of Erwinia as a co-obligate endosymbiont in Cinara aphids. Gordon Research Seminar on animal-microbe symbioses - initiation and maintenance of mutualisms. Mount Snow, West Dover, United States of America. | |
2015 | Manzano-Marín A, Simon J-C, and Latorre A. Snapshots of a shrinking partner. Gordon Research Conference on animal-microbe symbioses - identifying the common language of host-microbe associations. Waterville Valley, United States of America. |